Render, "As Babylon caused the slain of Israel to fall, so because of Babylon, hare fallen the slain of (or, in) the whole earth." Babylon has to answer for the general carnage caused by its wars.

As Babylon hath caused the slain of Israel,.... In Jerusalem, when that city was taken the Chaldeans, and destroyed:

so at Babylon shall all the slain of all the earth; or "land"; that is, the land of Chaldea; the inhabitants of which fled to Babylon upon the invasion of the Medes and Persians, both for their own safety, and the defence of that city; and where, being slain, they fell; and this was a just retaliation of them for what they had done to Israel. These words may be considered, as they are by some, as the song of the inhabitants of heaven and earth, observing and applauding the justice and equity of divine Providence in this affair; see Revelation 13:7.

As Babylon hath caused the {d} slain of Israel to fall, so at Babylon shall fall the slain of all the earth.

(d) Babylon not only destroyed Israel, but many other nations.

51:49 Of all the earth - This term must be understood in a restrained sense; the Chaldeans coming up from all parts of Chaldea to help Babylon, were slain there, as by the means of Babylon the Israelites were slain that came from all parts of Judea to help Jerusalem.

As...: or, Both Babylon is to fall, O ye slain of Israel, and with Babylon, etc

the earth: or, the country

49. caused . to fall-literally, "has been for the falling," that is, as Babylon made this its one aim to fill all places with the slain of Israel, so at Babylon shall all the slain of that whole land (not as English Version, "of all the earth") [Maurer]. Henderson translates, "Babylon also shall fall, ye slain of Israel. Those also of Babylon shall fall, O ye slain of all the earth." But, "in the midst of her," Jer 51:47, plainly answers to "at Babylon," Jer 51:49, English Version.

51:1-58 The particulars of this prophecy are dispersed and interwoven, and the same things left and returned to again. Babylon is abundant in treasures, yet neither her waters nor her wealth shall secure her. Destruction comes when they did not think of it. Wherever we are, in the greatest depths, at the greatest distances, we are to remember the Lord our God; and in the times of the greatest fears and hopes, it is most needful to remember the Lord. The feeling excited by Babylon's fall is the same with the New Testament Babylon, Re 18:9,19. The ruin of all who support idolatry, infidelity, and superstition, is needful for the revival of true godliness; and the threatening prophecies of Scripture yield comfort in this view. The great seat of antichristian tyranny, idolatry, and superstition, the persecutor of true Christians, is as certainly doomed to destruction as ancient Babylon. Then will vast multitudes mourn for sin, and seek the Lord. Then will the lost sheep of the house of Israel be brought back to the fold of the good Shepherd, and stray no more. And the exact fulfilment of these ancient prophecies encourages us to faith in all the promises and prophecies of the sacred Scriptures.