| Barnes' Notes on the Bible And the Lord have removed ... - The land shall be given up to desolation. The men - the strength of the nation - shall be taken to a distant land. And there be a great forsaking - A great desolation; the cities and dwellings shall be abandoned by the inhabitants; compare Isaiah 17:2; Jeremiah 4:29; Zephaniah 2:4.
Gill's Exposition of the Entire BibleAnd the Lord have removed men far away,.... Not to Babylon, but to the ends of the earth, into the most distant countries, by means of the Romans; for they were but instruments of carrying the Jews captive out of their own land, and dispersing them among the several nations of the world; it was the Lord's doing, and a judgment which he inflicted upon them for their sins: and there be a great forsaking in the midst of the land; not that there should be many left in the land, and multiply and increase in it; which is the sense of the Septuagint, Vulgate Latin, and Arabic versions; but that the land should be greatly forsaken of men; there should be many places in the midst of the land destitute of them; and this should continue a long time, as Kimchi observes, which therefore cannot be understood of the Babylonish captivity, but of their present one.
Geneva Study BibleAnd the LORD have removed men far away, and there be a great forsaking in the midst of the land.
Wesley's Notes 6:12 Removed - Hath caused this people to be carried away captive into far countries. A forsaking - 'Till houses and lands be generally forsaken of their owners.
Jamieson-Fausset-Brown Bible Commentary12. (2Ki 25:21). forsaking-abandonment of dwellings by their inhabitants (Jer 4:29).
Matthew Henry's Concise Commentary6:9-13 God sends Isaiah to foretell the ruin of his people. Many hear the sound of God's word, but do not feel the power of it. God sometimes, in righteous judgment, gives men up to blindness of mind, because they will not receive the truth in the love of it. But no humble inquirer after Christ, need to fear this awful doom, which is a spiritual judgment on those who will still hold fast their sins. Let every one pray for the enlightening of the Holy Spirit, that he may perceive how precious are the Divine mercies, by which alone we are secured against this dreadful danger. Yet the Lord would preserve a remnant, like the tenth, holy to him. And blessed be God, he still preserves his church; however professors or visible churches may be lopped off as unfruitful, the holy seed will shoot forth, from whom all the numerous branches of righteousness shall arise. | 
